This information is intended for U.S. audiences only.

Intended for U.S. audiences only

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Important Safety Information for Nabi-HB®

Important Safety Information
Nabi-HB, Hepatitis B Immune Globulin (Human)

What is the most important information I should know about Nabi-HB?
Nabi-HB® is prepared from blood plasma donated by individuals with high amounts of Hepatitis B antibodies. Products, like Nabi-HB, that are made from human plasma may contain infectious agents, like viruses. Human plasma is tested for viruses and treated to kill or remove certain, known viruses. There is still the possibility that these products can transmit disease caused by known and unknown infectious agents. Talk to your healthcare provider about the risks and benefits of using Nabi-HB.

Who should not use Nabi-HB?
Do not get a Nabi-HB injection if you:

  • Have had a severe allergic reaction to any human immune globulins
  • Are deficient in IgA antibodies.
  • Have severe thrombocytopenia (low blood platelets) or any blood clotting disorder.

What should I tell my healthcare provider before using Nabi-HB?

  • If you have an IgA deficiency
  • If you have severely low blood platelets or any blood clotting disorder
  • If you are scheduled to take vaccinations within 3 months of taking Nabi-HB
  • If you are pregnant
  • If you are breastfeeding
  • About all the medicines you take

What are the possible side effects of Nabi-HB?
Most side effects of Nabi-HB are mild. Side effects are grouped by how often they happen when you are treated.

Side effects are mostly local and include:

  • Swelling and redness at the injection site
  • Pain at the injection site
  • Headache
  • Muscle pain
  • General discomfort
  • Nausea
  • Vomiting
  • Higher than normal levels of liver enzymes
  • Bruising
  • Joint stiffness
  • Lower than normal levels of white blood cells
  • Higher than normal levels of creatinine

These are not all the possible side effects of Nabi-HB. Talk to your healthcare provider for any side effect that bothers you or does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

For more information call 1-800-458-4244.